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Natural Product Research 2018-Nov

Antibacterial and antifungal properties of crude extracts and isolated compounds from Lychnophora markgravii.

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Alvaro José Hernández Tasco
Román Yesid Ramírez Rueda
Carlos José Alvarez
Fabiana Terezinha Sartori
Ana Claudia B C Sacilotto
Izabel Yoko Ito
Walter Vichnewski
Marcos José Salvador

Keywords

Abstract

Antimicrobial activity of dichloromethane and ethanol extracts and five compounds: pinostrobin (I), pinocembrin (II), tectochrysin (III), galangin 3-methyl ether (IV) and tiliroside (V) isolated from Lychnophora markgravii aerial parts against fifteen microorganisms was determined. The structures of these compounds were elucidated based on ESI-MS and NMR spectroscopic data. Both extracts showed antimicrobial activity against several tested microorganisms. Pinostrobin, tectochrysin and galangin 3-methyl ether showed the strongest antibacterial and antifungal effects.

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