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Microbial Pathogenesis 2018-Aug

Antibacterial potential of silver nanoparticles synthesized using Madhuca longifolia flower extract as a green resource.

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Maheshkumar Prakash Patil
Rahul Dheerendra Singh
Prashant Bhimrao Koli
Kalpesh Tumadu Patil
Bapu Sonu Jagdale
Anuja Rajesh Tipare
Gun-Do Kim

Keywords

Abstract

The green and one-step synthesis of silver nanoparticles (AgNPs) has been proposed as simple and ecofriendly. In the present study, a flower extract of Madhuca longifolia was used for the reduction of silver nitrate into AgNPs, with phytochemicals from the flower extract as a reducing and stabilizing agents. The synthesized AgNPs were spherical and oval shaped and about 30-50 nm sizes. The appearance of a brown color in the reaction mixture is a primary indication of AgNPs formation, and it was confirmed by observing UV-visible spectroscopy peak at 436 nm. The Energy Dispersive X-ray spectra and X-ray diffraction analysis results together confirm that the synthesized nanoparticles contain silver and silver chloride nanoparticles. The Zeta potential analysis indicates presence of negative charges on synthesized AgNPs. The FT-IR study represents involvement of functional groups in AgNPs synthesis. Synthesized AgNPs shows potential antibacterial activity against Gram-positive and Gram-negative pathogens. M. longifolia flower is a good source for AgNPs synthesis and synthesized AgNPs are applicable as antibacterial agent in therapeutics.

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