Fitoterapia 2008-Dec

Antimicrobial and cytotoxic activities of Laportea crenulata.

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M Mukhlesur Rahman

Alam Khan

M Ekramul Haque

M Motiur Rahman

ARTICLE: 18621115

DOI: 10.1016/j.fitote.2008.04.007

BioSeek: 18621115

Keywords

Abstract

Crude extracts and 2alpha,3beta,21beta,24beta,28-pentahydroxy-olean-12-ene (1) obtained from the root of Laportea crenulata exhibited remarkable antibacterial activities against both Gram (+) and Gram (-) bacteria. The antifungal activities of crude extracts and compound (1) were also determined. The cytotoxic activities of crude extracts and compound (1) were observed by brine shrimp bioassay and LC(50) value of the compound (1) was found to be 27.54 microg/ml.

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Antimicrobial and cytotoxic activities of Laportea crenulata.

Keywords

laportea

antibacterial

antifungal

antibiotic

Abstract

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