Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 1995
[Antimutagenic properties of Angelica archangelica L].
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Keywords
Abstract
The antimutagenic activity of Angelica archangelica L. aqueous and alcohol extracts of thio-TEPA against mutagenicity was examined by the micronucleus test in murine bone marrow cells. The reduction of Thio-TEPA's mutagenic activity was more profound when the extracts were injected 2 hours before thio-TEPA treatment, as seen during simultaneous treatment. The observed reduction of micronuclear frequencies was as high as 77%.