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Chemical and Pharmaceutical Bulletin 1993-May

Astins A and B, antitumor cyclic pentapeptides from Aster tataricus.

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H Morita
S Nagashima
K Takeya
H Itokawa

Keywords

Abstract

Two novel antitumor chlorine- and alloThr-containing cyclic pentapeptides, named astins A and B, both of which were isomers and took a cis configuration in one of the amide bonds, were isolated from Aster tataricus together with astin C. Their structures were solved by spectroscopic analysis and chemical degradation.

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