International journal of immunopharmacology 1984
Augmentation of natural cell-mediated cytotoxic reactivity of mouse lymphoid cells by aloctin A.
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Keywords
Abstract
The levels of natural cell-mediated cytotoxicity could be augmented by administration of Aloctin A (Alo A), a lectin having anti-tumor activity. i.v. administration of Alo A induced augmentation of cytotoxicity by spleen cells and by peritoneal exudate cells (PEC). On the other hand, i.p. administration of Alo A induced augmentation of cytotoxicity by PEC but not by spleen cells. The effector cells seemed to be natural killer cells.