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Journal of Natural Products 2011-Oct

Biologically active arborinane-type triterpenoids and anthraquinones from Rubia yunnanensis.

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Jun-Ting Fan
Bin Kuang
Guang-Zhi Zeng
Si-Meng Zhao
Chang-Jiu Ji
Yu-Mei Zhang
Ning-Hua Tan

Keywords

Abstract

Twelve new arborinane-type triterpenoids (1-12) and four new anthraquinones (13-16), together with 50 known compounds, were isolated from the roots of Rubia yunnanensis. The structures of 1-16 were elucidated by spectroscopic data analysis and chemical methods. All compounds were evaluated for their cytotoxic, antibacterial, and antifungal activities. Rubiyunnanol C (5) is the first example of an arborinane-type triterpenoid with a double bond at C-8-C-9.

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