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Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 2007-Apr

[Bronchial asthma attack with lactic acidosis and hypokalemia in a case receiving high dose inhalation of procaterol hydrochloride].

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Satoshi Noma
Shingo Kubota
Kazuya Matsukizono
Asako Tanoue
Tomohiro Kumamoto
Tetsuhiko Taira
Hideo Mitsuyama
Toshihumi Kawabata
Takayuki Suetsugu
Jun Iwakaw

Keywords

Abstract

We report a case of bronchial asthma attack with lactic acidosis and hypokalemia in a patient receiving high-dose inhalation of procaterol hydrochloride. A 28-year-old man was transferred to our hospital because of adynamia, nausea and dyspnea. He had used inhaled procaterol hydrochloride with a pressurized metered dose inhaler about 20 times before admission. On admission, there were no signs of shock state or hypoxemia and laboratory data showed hypokalemia, hyperglycemia and metabolic acidosis with elevated anion gap. Lactic acidosis was identified as the reason for the metabolic acidosis with elevated anion gap. Lactic acidosis improved after 12 hours. Lactic acidosis due to high dose inhalation of procaterol hydrochloride was suggested.

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