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Ceylon Medical Journal 2008-Mar

Case of generalised myasthenia gravis with membranous nephropathy.

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K P Ruwan C Prasad
D G S Alahakoon
U Vidanagama

Keywords

Abstract

We report a 40-year old woman with bilateral partial ptosis, complete external ophthalmoplegia, and weakness and fatiguability of upper limbs. She was on treatment for hypertension for 5 months at the time of admission. She was found to have generalised myasthenia gravis and membranous nephropathy with end-stage renal disease. Her symptoms and signs improved within 2 months on treatment with neostigmine and prednisolone. It is postulated that either thymic hyperplasia or the subclinical stage of a thymoma may be the underlying aetiological factor in this patient.

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