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Natural Product Communications 2016-Mar

Chemical Composition of the Essential Oil from the Fresh Fruits of Xylopia laevigata and its Cytotoxic Evaluation.

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Emmanoel Vilaça Costa
Thanany Brasil da Silva
Cinara Oliveira D'Souza Costa
Milena Botelho Pereira Soares
Daniel Pereira Bezerra

Keywords

Abstract

The essential oil obtained by hydrodistillation from the fresh fruits of Xylopia laevigata was analyzed by gas chromatography using a flame ionization detector (GC-FID) coupled to a mass spectrometer (GC-MS). Monoterpenes predominated, forming 95.0% of the total essential oil. The major constituents identified were limonene (56.2%), α-pinene (28.0%), and β-pinene (5.5%). Cytotoxic activity against tumor cell lines and non-tumor cells was also investigated; however, neither the essential oil nor its major constituents evaluated presented any cytotoxic activity (IC₅₀ > 25.0 µg mL⁻¹).

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