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Yakugaku Zasshi 2003-Apr

[Constituents of the pericarps of Mallotus japonicus (Euphorbiaceae)].

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Munehisa Arisawa

Keywords

Abstract

Rottlerin-like phloroglucinol derivatives isolated from the pericarps of Mallotus japonicus Muell. Arg. (Euphorbiaceae) are reviewed. Chemical structures, cytotoxicity, antitumor and antitumor-promoting effects, antiviral activity, anti-HIV-RT activity, and inhibitory activity of activated macrophages (inhibitory activities of NO, prostaglandin E2, tumor necrosis factor-alpha, and interleukin-6 production) of the phloroglucinol derivatives are described.

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