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Multiple Sclerosis and Related Disorders 2016-Mar

Dengue fever in patients with multiple sclerosis taking fingolimod or natalizumab.

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Yara Dadalti Fragoso
Paulo Diniz da Gama
Sidney Gomes
Jussara Mathias Netto Khouri
André Palma da Cunha Matta
Maria Fernanda Mendes
Carla Renata Aparecida Vieira Stella

Keywords

Abstract

Dengue fever is the most prevalent mosquito-borne viral illness in humans. There may be different clinical manifestations of the disease, from mild symptoms to hemorrhagic forms of dengue fever and even neurological complications of this viral infection. Blood cells are usually affected, and thrombocytopenia is the hallmark of the disease. This paper presents 15 cases of dengue fever in patients with multiple sclerosis (MS) taking fingolimod or natalizumab. There were no complications of dengue fever or worse outcomes of MS in these patients, and only four of them needed short-term treatment withdrawal due to lymphopenia.

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