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Natural Product Communications 2014-Sep

Dipterostilbenosides A and B, oligostilbene glycosides from Dipterocarpus tuberculatus.

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Serm Surapinit
Jonkolnee Jong-aramruang
Pongpun Siripong
Suttira Khumkratok
Santi Tip-pyang

Keywords

Abstract

From the chemical investigation of the methanolic extract of the roots of the Thai dipterocarp, Dipterocarpus tuberculatus, two new oligostilbene glycosides, dipterostilbenes A (1) and B (2), were isolated together with four known stilbenes. Their structures and relative configurations were determined on the basis of spectroscopic data. From an evaluation of cytotoxic activity against KB and HeLa cell lines, α-viniferin (5) and (-)-hopeaphenol (6) showed potent activity, but less than that of doxorubicin.

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