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European journal of cancer & clinical oncology 1989-Dec

Effect of hyperthermia and/or nicotinamide on the radiation response of a C3H mammary carcinoma.

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E Kjellén
R W Pero
P Nilsson
S A Hill

Keywords

Abstract

The effect of hyperthermia and/or nicotinamide (200 mg/kg of body weight) on the tumour growth delay induced by radiation was evaluated in a C3H mouse mammary adenocarcinoma. The study showed a radiosensitizing effect of hyperthermia and of nicotinamide but the combination of all three modalitites showed no increased tumor growth delay compared to hyperthermia and radiation alone. The tumour growth delay induced by hyperthermia was not modified by nicotinamide.

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