Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 2003-Dec
[Effect of total triterpenes from Centella asiatica on the depression behavior and concentration of amino acid in forced swimming mice].
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Keywords
Abstract
OBJECTIVE
To evaluate the antidepressant activity of total triterpenes from Centella asiatica in forced swimming test.
METHODS
Mice were randomly divided into control group, model group and treatment group. The effect of total triterpenes from Centella asiatica on the immobility time in forced swimming mice and concentration of amino acid in mice brain tissue was observed.
RESULTS
Imipramine and total triterpenes from Centella asiatica reduced the immobility time and ameliorated the imbalance of amino acid levels.
CONCLUSIONS
The total triterpenes from Centella asiatica had antidepressant activity.
