Immunopharmacology

Enhancement of the immune response in mice by Astragalus membranaceus extracts.

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K S Zhao

C Mancini

G Doria

ARTICLE: 2149722

BioSeek: 2149722

Keywords

Abstract

Astragalus membranaceus extracts injected into normal mice or mice immunodepressed by cyclophosphamide or radiation treatment or by aging are able to enhance the antibody response to a T-dependent antigen. Optimal conditions for maximum effect have been established in normal C3H/HeJ and (C57B1/10 x DBA/2)F1 mice. Enhancement of the antibody response was associated with increase of Th cell activity in normal and immunodepressed mice. The biological activity of endotoxin-free extracts is dependent on the carbohydrate content.

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Enhancement of the immune response in mice by Astragalus membranaceus extracts.

Keywords

carbohydrate

astragalus trimestris

astragalus

Abstract

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