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Bulletin of Experimental Biology and Medicine 2012-Dec

Experimental study of the efficiency of impaza on the model of chronic aseptic prostatic inflammation.

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T G Borovskaya
T I Fomina
A V Pakhomova
L A Ermolaeva
M E Poluektova
E S Zhavbert
Ju L Dugina
I A Kheifets
O I Epstein

Keywords

Abstract

We compared the efficacy of Impaza (antibodies against endothelial NO-synthase in ultra-low doses) and Serenoa repens on the rat model of chronic aseptic prostatic inflammation. Administration of Serenoa repens in a dose of 50 mg/kg for 1.5 months prevented the development of prostate sclerosis and increased luminal area, but did delay the development of atrophic processes. In animals treated with Impaza (3 ml/kg for 1.5 months), atrophic changes in the prostate gland were practically absent. These findings indicate that Impaza can be used in complex therapy of abacterial prostatitis.

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