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Canadian Journal of Neurological Sciences 1996-Aug

Headache and scalp edema in sickle cell disease.

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G Pari
H M Schipper

Keywords

Abstract

BACKGROUND

Major neurological complications of sickle cell disease include cerebral infarction and intracranial hemorrhages.

METHODS

We describe the case of a 25-year-old man with sickle cell disease who developed a severe headache of acute onset, located at the vertex. There was associated pitting edema of the scalp.

RESULTS

Technetium and gallium bone imaging showed focal decreased uptake of the tracers, consistent with a recent fronto-parietal skull infarction. Management included intravenous hydration and analgesic medication.

CONCLUSIONS

In addition to the more common intracranail vaso-occlusive complications, skull infarction should be considered as a cause of newonset headache in patients with sickle cell disease, especially if scalp edema is present.

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