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JPMA. The Journal of the Pakistan Medical Association 2009-Sep

Hereditary prothrombin deficiency.

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Muzamil Shabana Ejaz
Nazia Latif
Ashraf Memon

Keywords

Abstract

Hereditary prothrombin deficiency is one of the rare congenital coagulation defects. We report a case of 4 months old child who initially presented at 11/2 month of age with high-grade fever, generalized convulsions and brownish aspirate through nasogastric tube, diagnosed and managed as meningitis and sepsis. He was readmitted at 4 months of age with bruises over legs. Coagulation profile was suggestive of common pathway defect. Further evaluation revealed absent prothrombin level while other factors were within normal limits.

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