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Phytochemistry 2015-Feb

Highly oxygenated sesquiterpenes in Artemisia alba Turra.

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Milka Todorova
Antoaneta Trendafilova
Kalina Danova
Luke Simmons
Evelyn Wolfram
Beat Meier
Rainer Riedl
Luba Evstatieva

Keywords

Abstract

Ten new sesquiterpene alcohols of which seven germacranes, a eudesmane, a guaiane and an oplopane were isolated from the aerial parts of Artemisia alba Turra. Their structures and relative stereochemistry were elucidated by spectral methods ((1)H and (13)C NMR, COSY, HSQC, HMBC, NOESY, and MS). In addition, the known 7-hydroxycadin-4-en-3-one, centaureidin and axillarin were found for the first time in the studied species.

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