Infection and Immunity 2005-Sep

Horizontally acquired genes for purine salvage in Borrelia spp. causing relapsing fever.

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Alan G Barbour

Adrienne D Putteet-Driver

Jonas Bunikis

ARTICLE: 16113341

DOI: 10.1128/IAI.73.9.6165-6168.2005

PMC: PMC1231056

BioSeek: 16113341

Keywords

Abstract

Unlike Borrelia burgdorferi, the relapsing fever agent Borrelia hermsii and the related Borrelia miyamotoi had purA and purB genes of the purine salvage pathway. These were located among the rRNA genes. Phylogenetic analysis indicated that these genes had a different evolutionary history than those of orthologs in other spirochetes.

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Horizontally acquired genes for purine salvage in Borrelia spp. causing relapsing fever.

Keywords

purine

lyme disease

fever

Abstract

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