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East African Medical Journal 1998-Nov

Human plasma derived hepatitis B vaccine: Kenyan experience.

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F A Okoth
P M Kaiguri
J Tuei
E M Mathenge
N O Ragot
G Kamau
J Kulundu
V Osidiana
A Njuguna
P M Tukei

Keywords

Abstract

OBJECTIVE

To determine the efficacy and safety of hepaccine B.

METHODS

Vaccination on first-come-first-served basis.

METHODS

Kenya Medical Research Institute (KEMRI) staff and families at Nairobi, Kenya.

METHODS

A total of 107 vaccinees aged 0-10 years and 10 years and above.

RESULTS

Antibody to hepatitis B surface antigen (anti HBs) checked one month after the third dose of the vaccine.

RESULTS

Ninety seven per cent of the vaccinees developed antiHBs. Side effects were few in the form of soreness at site of injection and headache.

CONCLUSIONS

Hepaccine B produced good immune response in vaccinees with minimal side effects.

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