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Archives of Gynecology and Obstetrics 2008-Apr

Massive ovarian edema in pregnancy after ovulation induction using clomiphene citrate.

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Ryuji Kawaguchi
Sachiyo Ueda
Yoriko Tsuji
Shoji Haruta
Seiji Kanayama
Yoshihiko Yamada
Hidekazu Ooi
Hiroshi Kobayashi

Keywords

Abstract

BACKGROUND

Massive ovarian edema is a benign enlargement of the ovary caused by accumulation of fluid occurring mainly in young women. Most cases are thought to result from venous and lymphatic obstruction.

METHODS

We treated a 40-year-old multiparous pregnant woman with massive ovarian edema who had been received clomiphene citrate. She was admitted at 13th week of pregnancy for acute pelvic pain. Left oophorectomy was performed, and pathologic examination disclosed massive ovarian edema. Our report is the first case of massive ovarian edema with pregnancy after ovulation induction using clomiphene citrate.

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