Ancient science of life 2004-Apr
Modulatory effects of lxora coccinea flower on Cyclophosphamidetoxicity in tumour bearing mice.
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Abstract
The active fraction (AF) from lxora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour bearing mice, treated with cyclophosphamide (CYP). It also significantly increased the life span of tumour bearing mice, treated with cyclophosphamide. Serum glutamate pyruvate transaminase (SGPT) and serum alkaline phosphatase (SAKP) levels of tumour bearing mice treated with CYP were decreased significantly by combination therapy with I.coccinea AF. indicating protection against hepatic toxicity.