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American Journal of Ophthalmology 2006-Aug

Multifocal choroiditis in disseminated Cryptococcus neoformans infection.

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Carla Andreola
Maria P D Ribeiro
Carla R S de Carli
Ana Luisa F Gouvea
André L L Curi

Keywords

Abstract

OBJECTIVE

To report an uncommon case of multifocal choroiditis as the result of disseminated Cryptococcus neoformans infection in a patient who is HIV-positive.

METHODS

Interventional case report.

METHODS

A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and revealed C neoformans infection. Her condition evolved with sudden bilateral blindness and deafness. Ophthalmologic examination revealed multiple yellowish choroidal lesions in the posterior pole of both eyes.

RESULTS

Postmortem examination showed disseminated C neoformans infection. Histologic examination of the eyes confirmed the presence of C neoformans in the choroiditis.

CONCLUSIONS

Multifocal choroiditis in C neoformans infection is a rare ophthalmic manifestation. The recognition of this condition by ophthalmologists can help physicians to diagnose a disseminated and fatal disease.

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