Natural Product Research 2013

One new antitumour cassane-type diterpene from Caesalpinia crista.

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Qi-Jian Tian

Yang-Hui Ou

Xing-Bing He

Yong-Dong Jiang

ARTICLE: 22578007

DOI: 10.1080/14786419.2012.676551

BioSeek: 22578007

Keywords

Abstract

1α-acetoxy-5α, 7β-dihydroxycassa-11,13(15)-diene-16,12-lactone, a new cassane-type diterpene was isolated from Caesalpinia crista. The structure of this compound was elucidated by analysis of NMR spectra, and the relative configuration was established by NOE experiment. The new compound was evaluated for antitumour activity against T47D, DU145 and showed significant inhibitory activities.

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One new antitumour cassane-type diterpene from Caesalpinia crista.

Keywords

lactone

diterpene

caesalpinia

caesalpinia crista

anticancer

Abstract

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