Onset of HLA-B27-associated diseases in diabetic patient during a period of religious fasting: A case report.
Keywords
Abstract
BACKGROUND
The association between human leukocyte antigen B27 (HLA-B27) with its associated diseases is far from complete. The role of HLA-B27 in disease susceptibility is still not known, although many suggestions have been proposed.
UNASSIGNED
The patient was a 46-year-old policeman with a history of obesity, diabetes, and hypertension. He was a Shaolin lay disciple who fasted at the Shaolin temple for at least 1 week each year since 2014.
UNASSIGNED
The patient suffered three different HLA-B27-associated diseases including acute anterior uveitis, ulcerative colitis, and ankylosing spondylitis, from 2014 to 2016 because of prolonged fasting.
METHODS
The patient accept standard treatment after the diagnosis of acute anterior uveitis, ulcerative colitis, and ankylosing spondylitis.
RESULTS
The patient's symptoms and signs of acute anterior uveitis, ulcerative colitis, and ankylosing spondylitis were all relieved within one week after the clinical treatment.
CONCLUSIONS
Our case suggested that prolonged fasting may lead to the onset of HLA-B27-associated diseases in diabetic patient.
