[Pharmacological study on the extracts from Typhonium flagelliforme Blume].
Keywords
Abstract
OBJECTIVE
To study the pharmacological action of Typhonium flagelliforme Blune(TFB).
METHODS
Relieving a cough and eliminating expectoration were observed by strong aqua spray and pheol red determining methods. The antiasthmatic action was observed by whole spraying method. The analgesia and anti-inflammation were studied by the twisting test induced by acetic acid and ear swelling induced by xylene. The sedation was determined by autonomic action test. The toxicity of TFB was studied through the acute toxicity test in mice.
RESULTS
All the water, alcohol and ester extracts of TFB could significantly decrease cough times, increase phenol red outage in trachea, prolong asthma incubation period, decrease twisting times, inhibit ear swelling and decrease autonomic action times.
CONCLUSIONS
All water, alcohol and ester extracts of TFB have effects of relieving a cough, eliminating expectoration, antiasthmatic, analgesia, anti-inflammation and sedation. The maximum tolerances of TFB for acute toxicity were 720 g/kg(water extract), 900 g/kg (alcohol extract) 3240 g/kg(ester extract) respectively.
