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Journal of Medicinal Food 2008-Mar

Phytochemical investigation on leaf extract of Cordia salicifolia Cham.

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Luigi Menghini
Francesco Epifano
Lidia Leporini
Rita Pagiotti
Bruno Tirillini

Keywords

Abstract

The dichloromethane extract of leaves of Cordia salicifolia Cham. (Family Boraginaceae) was fractionated by SiO(2) column chromatography and analyzed by gas chromatography, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. The apolar extract is characterized by a very high content of (+)-spathulenol (0.53%). The major component of the extract exhibited a very weak activity as an inhibitor of growth of Helicobacter pylori in vitro (minimum inhibitory concentration = 200 microg/mL).

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