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International Journal of Hematology 2009-Apr

Portal hypertension resulted from paroxysmal nocturnal hemoglobinuria: a case report and review of literature.

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Da-long Yin
Lian-xin Liu
Shu-geng Zhang
Lan-tian Tian
Zhao-yang Lu
Hong-chi Jiang

Keywords

Abstract

Paroxysmal nocturnal hemoglobinuria is a rare intravascular hemolytic anemia, and thrombosis is the leading cause of mortality rate. The hepatic veins is the common site where Budd-Chiari syndrome usually occurs. We confronted a patient who simultaneously happened to have portal vein and superior mesenteric vein thrombosis leading to prehepatic portal hypertension and upper gastrointestinal bleeding. Percutaneous thrombolysis is an efficacious treatment.

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