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Revista Medica de Chile 2012-Sep

[Positron emission tomography with fluorine-deoxyglucose in sarcomas and non-sarcoma non-epithelial tumors].

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Teresa Massardo
María Josefina Jofré
María Paulina Sierralta
José Canessa
Gabriel Castro
Isabel Berrocal
Iván Gallegos

Keywords

Abstract

BACKGROUND

The usefulness of positron emission tomography (PET) with fluorine-deoxyglucose (FDG) in sarcomas and non-sarcoma non-epithelial (NSNE) tumors is not clearly defined.

OBJECTIVE

To report a Chilean experience with NSNE tumors evaluated using PET with FDG.

METHODS

Retrospective review of the database of a PET laboratory. Demographic data, indications and metabolic findings were compared with conventional imaging in 88 adults and children with diverse bone and soft tissue sarcomas as well as 24 gastrointestinal stromal tumors (GIST), 6 pleural malignant mesotheliomas in adults, and 9 medulloblastomas in children.

RESULTS

FDG showed good concordance with conventional imaging in NSNE tumors. It was helpful for staging, restaging, follow-up after treatment and for the detection of new not previously suspected lesions.

CONCLUSIONS

PET with FDG could have a prognostic role and help in patient management, mainly in musculoskeletal and high grade or less differentiated sarcomas. In GIST, it was a good tool for immunotherapy control.

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