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Arquivos Brasileiros de Cardiologia 2010-Oct

Profile of patients with hypertension included in a cohort with HIV/AIDS in the state of Pernambuco, Brazil.

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Evanizio Roque de Arruda Júnior
Heloisa Ramos Lacerda
Líbia Cristina Rocha Vilela Moura
Maria de Fátima Pessoa Militão de Albuquerque
Demócrito de Barros Miranda Filho
George Tadeu Nunes Diniz
Valéria Maria Gonçalves de Albuquerque
Josefina Cláudia Zirpoli Amaral
Verônica Soares Monteiro
Ricardo Alencar de Arraes Ximenes

Keywords

Abstract

BACKGROUND

Hypertension (HBP) is modifiable risk factor, whose control may reduce cardiovascular disease in patients with human immunodeficiency virus (HIV).

OBJECTIVE

To estimate the prevalence of hypertension and describe the characteristics of patients with hypertension infected by HIV/AIDS.

METHODS

A cross-sectional study aligned to a cohort of patients with HIV/AIDS. The study considered hypertension at levels > 140/90 mmHg or use of antihypertensive drugs and pre-hypertension at levels > 120/80 mmHg.

RESULTS

Out of 958 patients, 388 (40.5%) were normotensive, 325 (33.9%) were pre-hypertensive, and 245 (25.6%) were hypertensive. Out of these 245 patients, 172 (70.2%) were aware of the fact there they were hypertensive, and 36 (14.8%) had blood pressure controlled. Sixty-two (62) patients (54.4%) were diagnosed with hypertension after HIV diagnosis. Lipodystrophy occurred in 95 (46.1%) patients; overweight/obesity in 129 (52.7%). Use of antiretrovirals occurred in 184 (85.9%), 89 (41.6%) with protease inhibitors (PI) and 95 (44.4%) without PI. Out of these patients, 74.7 used antivirals > 24 months. Age, family history of hypertension, waist circumference, body mass index and triglyceride levels were higher among hypertensive patients. Time of HIV infection, CD4 count, viral load, time and type of antiretroviral regimen were similar in hypertensive and prehypertensive patients.

CONCLUSIONS

The high frequency of uncontrolled hypertensive patients and cardiovascular risks in HIV-infected patients point out to the need for preventive and therapeutic measures against hypertension in this group.

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