Journal of Natural Products 2004-Nov
Quinolone alkaloids with nitric oxide production inhibitory activity from Orixa japonica.
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Keywords
Abstract
Four new quinolone alkaloids, orixalone A (1), B (2), C (3), and D (4), together with 12 known compounds were isolated from the stems of Orixa japonica. Orixalone A (1) inhibited nitric oxide production in murine macrophage-like RAW 264.7 cells stimulated with interferon-gamma and lipopolysaccharide.