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Mini reviews in medicinal chemistry 2017

Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound.

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Shaoping Wu
Yaoyao Ning
Yingyong Zhao
Wenji Sun
Serge Thorimbert
Luc Dechoux
Matthieu Sollogoub
Yongmin Zhang

Keywords

Abstract

Gentiopicroside is a secoiridoid compound isolated from Gentiana lutea which is called Qin Jiao in Chinese. It is one of the most common herbal medicines used in China. In this article, we review the pharmacological and biological activity (antiviral, anti-inflammatory, analgesia, antihepatotoxic and choleretic), as well as biotransformation of the gentiopicroside. In addition, attempt towards the total synthesis of gentiopicroside is also presented.

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