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Pediatric Transplantation 2006-May

Rothia dentocariosa sepsis in a pediatric renal transplant recipient having post-transplant lymphoproliferative disorders.

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Silke Wiesmayr
Ingrid Stelzmueller
Natalie Berger
Therese C Jungraithmayr
Manfred Fille
Miriam Eller
Lothar Bernd Zimmerhackl
Raimund Margreiter
Hugo Bonatti

Keywords

Abstract

BACKGROUND

Rothia dentocariosa (RD) is a Gram-positive rod that colonizes the human oral cavity and can cause infective endocarditis.

RESULTS

We report on a six-yr-old boy who underwent renal transplantation for polycystic kidney disease at the age of eight months. He developed post-transplant lymphoproliferative disorders after four yr and progressive graft failure. Following chemotherapy, the patient presented with neutropenia and sepsis. RD was isolated from blood and treatment with piperacillin/tazobactam was initiated; however, the child died because of multiorgan failure.

CONCLUSIONS

To the best of our knowledge, this is the first case of RD sepsis in a pediatric solid organ transplant recipient.

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