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Journal of Medicinal Food

Secondary metabolites of Miconia rubiginosa.

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Juliana Rodrigues
Daniel Rinaldo
Marcelo Aparecido da Silva
Lourdes Campaner dos Santos
Wagner Vilegas

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Abstract

The Miconia genus is the most representative of the Melastomataceae family, and some species are commonly used in Brazilian folk medicine as anti-inflammatory agents. In this work we investigated the leaves from Miconia rubiginosa (Bonpl.) DC, using high-speed countercurrent chromatography, which yielded 11 substances (eight flavonoids, gallic acid, casuarictin, and schizandriside). Identification was achieved using nuclear magnetic resonance spectroscopy and high-performance liquid chromatography-circular dichroism-diode array detection analyses.

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