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Medicinski Arhiv 2006

[Sepsis--clinical parameters of recognition and differentiation].

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Nada Koluder

Keywords

Abstract

BACKGROUND

Even today, early recognition of sepsis remains a great problem, requiring the search for clinical symptoms and signs with predictive features.

OBJECTIVE

to define the number of days of disease till hospitalization and value of some clinical signs in recognition and differentiation of patients with monomicrobial (M.A) gram positive and gram negative sepsis.

METHODS

200 patients with clear clinical and laboratory signs of sepsis, septic shock and monomicrobial aerobic bacterial isolate were included randomly. Patients are divided into two equal groups.

RESULTS

patients with gram negative (m.a.) sepsis are hospitalized earlier relating to patients with gram positive sepsis (X2= 24,345; p< 0.001). Significance of differences in two basic groups of sepsis is the most evident for heart murmur (t=6,703; p<0,0001), shivers (t=3,313; p<0,001), afebrility (t=16,148; p<0,001), fatigue-exhaustion (t=4,472; p<0,001), pulmonary manifestations (t=3,497; p<0,001).

CONCLUSIONS

results of investigation show the recognition of clinical symptoms and signs of sepsis, which enables the differentiation between gram positive and gram negative. Initially, this provides clinicians with a greater therapeutic reliability.

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