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Pediatrics International 2014-Apr

Streptococcus gallolyticus subsp. pasteurianus meningitis in an infant.

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Yoshiko Takahashi
Naruhiko Ishiwada
Junko Tanaka
Kiyofumi Okusu
Sadahiro Ichimura
Haruka Hishiki
Setsuo Ota
Yoichi Kohno

Keywords

Abstract

Streptococcus gallolyticus subsp. pasteurianus was formerly classified as S. bovis biotype II/2, which is recognized as a rare cause of neonatal sepsis and meningitis. Since the taxonomy classification change, there have not been many reports of meningitis due to S. gallolyticus subsp. pasteurianus. Moreover, the pathogenesis of late onset S. gallolyticus subsp. pasteurianus meningitis in infants is unclear. Here we report a case of meningitis in a 5-week-old infant with preceding diarrhea. S. bovis biotype II/2 was isolated from the blood, cerebrospinal fluid and stool, and then was identified as S. gallolyticus subsp. pasteurianus on 16S rRNA gene sequencing. Isolates from all three sample types had identical profiles on pulsed-field gel electrophoresis. The intestinal tract was thought to be the source of the infection.

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