Archives of Pharmacal Research 1998-Oct

Structural analogues of cumambrin B from the flower of Chrysanthemum boreale.

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D S Jang

M S Yang

T J Ha

K H Park

ARTICLE: 9875500

BioSeek: 9875500

Keywords

Abstract

The structural analogues of cumambrin B (1, 2, 3, 4) were isolated from the flower of Chrysanthemum boreale Makino. The structures of compounds were determined by two-dimensional 1H-1H COSY and 13C-1H COSY spectra with the aid of homonuclear and heteronuclear double resonance experiment. The stereochemistry of compounds has been verified from single crystal X-ray diffraction of cumambrin A (2). The antimicrobial activities of these guaianolides have been studied.

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Structural analogues of cumambrin B from the flower of Chrysanthemum boreale.

Keywords

cumambrin a

cumambrin b

guaianolide

chrysanthemum

tanacetum vulgare

tanacetum

Abstract

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