Yao xue xue bao = Acta pharmaceutica Sinica 1989
[Studies on synthesis of baogongteng A--a new myotic agent].
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Keywords
Abstract
Baogongteng A, isolated from Erycibe obtusifolia Benth., is a new tropane alkaloid used for treating glaucoma. Using synthetic 6 beta-acetoxy-tropinone as starting material, racemic Baogongteng A(8) was synthesized. Synthetic Baogongteng A also shows myotic activities in rabbits, but the potency is half of that of the natural product.