Acta Poloniae Pharmaceutica
Synthesis, structural characterization and antimicrobial studies of hydrazone derivatives of 3-hydroxyimino-5-methyl-2-hexanone.
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Abstract
The derivatives of 3-hydroxyimino-5-methyl-2-hexanone oxime have been obtained in good yield by its reactions either with hydrazine hydrate or phenyl hydrazine, respectively. IR and 1H NMR spectral data of these compounds have been discussed. All the newly synthesised compounds have been tested for their biological activity against S. auerus, S. typhi, C. albicans, A. niger, S. cerevisiae and M. tuberculosis H47RV.