Pediatrics 1980-Mar
Theophylline-induced seizures in accidentally overdosed neonates.
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Abstract
Theophylline-induced seizures are reported in two neonates. The serum theophylline concentration during seizures were 51.0 mg/liter and 54.0 mg/liter. Toxic symptoms prior to seizures may be absent or undetected, suporting the necessity of blood level monitoring during theophylline therapy.