Journal of Natural Products 2010-Jul

Triterpene saponins from Clematis chinensis and their potential anti-inflammatory activity.

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Qiang Fu

Ke Zan

Mingbo Zhao

Sixiang Zhou

Shepo Shi

Yong Jiang

Pengfei Tu

ARTICLE: 20540535

DOI: 10.1021/np100057y

BioSeek: 20540535

Keywords

Abstract

Seven new triterpene saponins, clematochinenosides A-G (1-7), together with 17 known saponins (8-24), were isolated from the roots and rhizomes of Clematis chinensis. Their structures were elucidated on the basis of spectroscopic evidence and hydrolysis products. Compounds 1, 3-7, and 20-24 showed inhibitory activities against COX-1 and COX-2 enzymes.

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Triterpene saponins from Clematis chinensis and their potential anti-inflammatory activity.

Keywords

saponin

triterpene

inflammation

clematis

clematis chinensis

anti inflammatory

Abstract

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