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Food and Chemical Toxicology 2017-Nov

Triterpenes from Pouteria ramiflora (Mart.) Radlk. Leaves (Sapotaceae).

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Patrícia Marques Rodrigues
João Victor Dutra Gomes
Claudia Masrouah Jamal
Álvaro Cunha Neto
Maria Lucilia Santos
Christopher William Fagg
Yris Maria Fonseca-Bazzo
Pérola de Oliveira Magalhães
Paloma Michelle de Sales
Dâmaris Silveira

Keywords

Abstract

Pouteria ramiflora (Mart.) Radlk. (Sapotaceae) is a species used by inhabitants from the Cerrado for its edible fruits and medicinal value. Hexane crude extracts from leaves and fractions were evaluated for in vitro α-amylase inhibitory activity and antioxidant potential. The fraction with the highest α-amylase inhibitory activity was submitted to a phytochemical study. Three triterpenes were isolated, friedelin, epi-friedelanol, and taraxerol. This is the first report of these compounds isolated from P. ramiflora. Moreover, this is the first report of friedelin isolated from Pouteria sp. Epi-friedelanol was present in significant amounts, suggesting that this compound could be a candidate marker for this species.

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