Journal of Asian Natural Products Research 2016

Two new lignans from twigs of Aglaia odorata.

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Lei Peng

Wu-Xiang Fu

Chun-Xia Zeng

Lin Zhou

Mei-Fen Bao

Xiang-Hai Cai

ARTICLE: 26207974

DOI: 10.1080/10286020.2015.1057575

BioSeek: 26207974

Keywords

Abstract

HPLC-guided separation of twigs of Aglaia odorata led to the isolation of eight lignans, including two new ones, 3'-methoxy-N-demethylrocaglamide (1) and 4'-O-demethyl-deacetylaglaxiflorin A (2). Compound 1 showed excellent cytotoxicity against three human cancer cell lines, HeLa, SGC-7901 gastric cancer, and A-549 lung cancer with the values of 0.32, 0.12, and 0.25 μM, respectively.

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Two new lignans from twigs of Aglaia odorata.

Keywords

lignan

lung neoplasms

neoplasms

aglaia odorata

aglaia

Abstract

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