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Saudi Journal of Biological Sciences 2020-Feb

In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens.

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Asad Syed
Natarajan Benit
Abdullah Alyousef
Abdulaziz Alqasim
Mohammed Arshad

Keywords

Abstract

The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectively. Antimicrobial potentials of the extracts were determined by performing the disc diffusion techniques. Results revealed that different organic solvents extracts namely methanol, ethanol and ethyl acetate extracts documented comparatively good activity against the studied microbial strains. The methanol extract of leaves of T. procumbens showed combatively better antioxidant potential. The tested plant leaf extract showed high activity against human lung cancer cells than breast cancer cell lines. 250 µg/ml plants extract showed 84 ± 2.8% toxicity against human lung cancer cells.

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