10 deacetylbaccatin iii/lung neoplasms

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Second generation taxanes: from the natural framework to the challenge of drug resistance.

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Taxanes represent the most important class of antitumor agents introduced in cancer therapy in the last decade. The first member of the family was paclitaxel, firstly isolated from Taxus Brevifolia and found active as antitumor agent at the end of 60's. In the mid of 90's, a semi-synthetic taxane

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