2 4 dihydroxychalcone/leukemia

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Synthesis and structure-activity relationship studies of furan-ring fused chalcones as antiproliferative agents.

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As part of our continuing investigation of flavonoid derivatives as potential anticancer substances, the synthesis of 25 cinnamoyl derivatives of benzofuran as furan-fused chalcones was carried-out and these compounds were further evaluated for their antiproliferative activity towards HL60

Antibacterial and Cytotoxic Activity of Compounds Isolated from Flourensia oolepis.

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The antibacterial and cytotoxic effects of metabolites isolated from an antibacterial extract of Flourensia oolepis were evaluated. Bioguided fractionation led to five flavonoids, identified as 2',4'-dihydroxychalcone (1), isoliquiritigenin (2), pinocembrin (3), 7-hydroxyflavanone (4), and

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