General toxicity (A) and vein damaging properties (B) of 5-hydroxymethyl-2-furfural (HMF) were studied in rabbits. A. 400 mg HMF was given as subcutaneous injections twice a day for a week. It was not possible to demonstrate any harmful effect of the injections on the following parameters: weight,
The aim of this paper is to evaluate the protective effect of 5-hydroxymethyl-2-furfural (5-HMF) on acute alcohol-induced liver oxidative injury in mice. 5-HMF, a maillard reaction product, was isolated from the fruits of Schisandra chinensis for animal experiments. Experimental ICR mice were
In an attempt to find new types of anti-hypoxic agents from herbs, we identified 5-hydroxymethyl-2-furfural (5-HMF) as a natural agent that fulfills the criterion. 5-HMF, the final product of carbohydrate metabolism, has favorable biological effects such as anti-oxidant activity and inhibiting
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