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acetylsalicylic acid/atrophy
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[Does acetylsalicylic acid and vitamin K antagonists are risk factors of macular degeneration related with age?].
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OBJECTIVE
The aim of this study was to evaluate the effects of chronic use of acetylsalicylic acid (ASA) and vitamin K antagonists (VKA) on the incidence of age related macular degeneration (AMD).
METHODS
The study included 292 individuals (187 women, 105 men, aged 45-94 (mean 73.2 ± 10.2 years).
[Protective action of acetylsalicylic acid in post-traumatic degeneration of rabbit articular cartilage].
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Acetylsalicylic acid as an adjuvant therapy for schizophrenia.
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BACKGROUND
Findings from both epidemiological and basic research point to the possibility that NSAIDS impede the deterioration in schizophrenia.
METHODS
To study the efficacy of acetylsalicylic acid we will perform a randomized placebo controlled double-blind add-on trial of 80 inpatients and
Cyclooxygenase inhibition aggravates pulmonary hypertension and deteriorates gas exchange in canine pulmonary embolism.
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We examined the effects of cyclooxygenase inhibitors on pulmonary hemodynamics and gas exchange after experimental acute pulmonary embolism in 12 intact anesthetized dogs. Pulmonary hemodynamics were evaluated by pulmonary arterial pressure (Ppa)/cardiac output (Q) plots before and 60 min after
Characterization of the adipose tissue atrophy induced by peroxisome proliferators in mice.
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In the present study, we characterized the effects of peroxisome proliferators (PP) on adipose tissue in mice. Treatment with potent PP, such as perfluorooctanoic acid (PFOA), 2-methyl-2-(p(1,2,3,4-tetrahydroxy-naphthyl)-phenoxy)propionic acid, (4-chloro-6-(2,3-xylidino)2-pyrimidinylthio) acetic
[Does acetylsalicylic acid have a negative influence on photodynamic therapy?].
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BACKGROUND
Non-thermal photodynamic therapy (PDT) is presently being used for the treatment of certain forms of age-related macular degeneration (AMD). This therapy results in selective occlusion of newly growing vessels. Due to this effectiveness of PDT the question came up whether inhibitors of
[Effect of pentoxyl, ibuprofen and acetylsalicylic acid on the thymus, spleen and adrenals in an experiment].
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The effect of acetylsalicylic acid, ibuprofen and pentoxyl on the histological and morphometric pattern of the thymus and the weight of the thymus and spleen was studied in rats. There was decreased function of the thymus and its atrophy with acetylsalicylic acid and ibuprofen. Pentoxyl increased
Reocclusion prophylaxis with dipyridamole combined with acetylsalicylic acid following PTA.
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After primary successful PTA, 199 patients were randomized into one of three treatment groups, namely, placebo or a combination of 75 mg dipyridamole with either 330 mg (high dose) or 100 mg (low dose) acetylsalicylic acid (ASA) tid. The duration of treatment was six months. Of the 199 patients
[Optic neuropathy in type-1 diabetes and acetylsalicylic acid-refractory thrombocyte activation].
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A 26-year-old female with severe complications from type I diabetes mellitus of 17 years' duration (proliferative retinopathy, nephropathy with renal failure and nephrotic syndrome) developed rapid deterioration of vision in the right eye to 6/60 over a period of several weeks. There were no other
Histopathological, ultrastructural, and immunohistochemical assessment of hippocampus structures of rats exposed to TCDD and high doses of tocopherol and acetylsalicylic acid.
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The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on central nervous system consists of changing expression of estrogen receptors, whereas the result of chronic inflammatory reaction caused by dioxin is occurrence of destructive changes in various organs connected with disturbed metabolism of
Comparison between zofenopril and ramipril in combination with acetylsalicylic acid in patients with left ventricular systolic dysfunction after acute myocardial infarction: results of a randomized, double-blind, parallel-group, multicenter, European study (SMILE-4).
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BACKGROUND
Angiotensin-converting enzyme inhibitors (ACEIs) are largely employed for treating patients with left ventricular dysfunction (LVD), but their efficacy may be negatively affected by concomitant administration of acetylsalicylic acid (ASA), with some difference among the different
Effect of acetylsalicylic acid on renal function in systemic lupus erythematosus.
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Glomerular filtration rate (GFR; 51Cr-EDTA clearance), serum creatinine concentration and urinary excretion of prostaglandins were measured in 8 patients with systemic lupus erythematosus (SLE) before and after 2 weeks of treatment with acetylsalicylic acid (ASA). ASA 65 mg/kg or up to 4 g/daily was
[Acetylsalicylic acid effects on pain sensitivity to myocardial ischemia and skin sensitivity in patients with angina pectoris].
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OBJECTIVE
To clarify if pain-relieving action of acetylsalicylic acid (ASA) is associated with lowered sensitivity of anginal patients to pain due to myocardial ischemia.
METHODS
A double blind randomized placebo-controlled trial enrolled 10 males aged 42-69 years with stable effort angina (EA) of
Does the use of acetylsalicylic acid have an influence on our vision?
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OBJECTIVE
Acetylsalicylic acid (ASA) is one of the most commonly used drugs in the world due to its anti-inflammatory, analgesic, and antipyretic properties. This review aims to describe the relationship between acetylsalicylic acid and age-related macular degeneration (AMD) - a chronic disease that
The role of retinol in, and the action of anti-inflammatory drugs on, hereditary retinal degeneration.
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Light deprivation retarded retinal degeneration in albino dystrophic rats. In pigmented dystrophic rats the presence of pigment in the eye retarded the degenerative process. Retinol labilized rat retinal lysosomes in vitro. Acetylsalicylic acid stabilized retinal lysosomes even in the presence of
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